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What do we know about the effects of marijuana on a teenager’s mind and body? What does science say?

“The science is clear about the effects of marijuana on two critical brain development periods,” said Dr. Sheryl R. Ryan, a fellow of the American Academy of Pediatrics. “One is during fetal growth, and the second is during adolescence.”

Ryan said that data shows that developing brains until the mid-20s can be vulnerable to the psychoactive component of cannabis, THC.

“THC, that crosses the blood-brain barriers, attaches itself to the cannabinoid receptive sites that are present in our brains and that THC hijacks those natural cannabinoids we have in our systems that are important for a variety of functions and hijacks them and maybe disrupts a bit of that normal brain development we see during adolescence or young adulthood,” Ryan explained.

She said: “We see memory deficits in kids who are heavy users.” We see memory deficits. We see what we call Amotivational Syndrome where kids perform worse in school. We also see cognitive difficulties, and we are also seeing higher rates of anxiety and depression, especially among young people with a family history which makes them vulnerable.”

We don’t know what the long-term effects of the disease will be.

Dr. Ryan Marino is a Cleveland medical toxologist, addiction specialist, and emergency medicine physician. He said, “Those receptors play a role in the development of the brain, and they also play a number of roles in your neurologic system, and in the body as a whole, and are not fully understood.” “I think that one of the main concerns is the interplay between adding cannabis to the body and the way these receptors are signaling and developing during brain growth. We don’t know the answer yet.”

Scott Osiecki, CEO of the ADAMHS Board in Cuyahoga County, said that they are a resource for people to understand and overcome addiction.

“For many years, people believed that marijuana was not addictive. But now, we know that one in ten people can become addicted. And if they begin before the age 18, it’s one in six,” Osiecki explained.

Doctors say longitudinal studies are needed to answer questions about the long-term effects of marijuana on developing brains.

The ABCD Study is currently underway at the National Institute of Health. The ABCD Study is the nation’s largest long-term brain development and child-health study. It follows almost 12,000 9 to 10-year olds through adulthood to determine how marijuana use, among other things, affects their brains, bodies and overall quality of living.

Ryan is concerned that the science will be lost in the messaging. Legalization without education may lead to young people believing marijuana is risk-free.

She asked, “How can you make young people realize that they may use it differently than adults?”

Doctors also said that more research is needed to take into account the potency of marijuana and the various ways in which it can be consumed and dosed.

What about marijuana-based medicines for children?

The FDA approved a drug containing a purified CBD that has shown to be effective at controlling certain seizures. Two FDA-approved THC medications are also available to treat nausea caused by chemotherapy.

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